Others

DL-2-AMINOOCTANOIC ACID

  • CAS:644-90-6
  • purity:99%
Inquiry

Quality Factory Supply 99% Pure DL-2-AMINOOCTANOIC ACID 644-90-6 with Efficient Delivery

  • Molecular Formula: C8H17NO2
  • Molecular Weight: 159.228
  • Appearance/Colour: White powder 
  • Melting Point: 260 °C (dec.)(lit.) 
  • Refractive Index: 1.4630 (estimate) 
  • Boiling Point: 267.8 °C at 760 mmHg 
  • PKA: 2.55±0.24(Predicted) 
  • Flash Point: 115.8 °C 
  • PSA: 63.32000 
  • Density: 0.999 g/cm3 
  • LogP: 2.06900 

DL-2-AMINOOCTANOIC ACID(Cas 644-90-6) Usage

General Description

DL-2-Aminooctanoic acid (also known as α-aminooctanoic acid) is an α-amino fatty acid used in the synthesis of polyoxin L analogues with potential anticandidal activity. In this study, it was incorporated into dipeptidyl polyoxin L derivatives to enhance affinity for peptide transport systems and stability against intracellular degradation in *Candida albicans*. The resulting analogues demonstrated inhibitory effects on chitin synthetase and were recognized by the fungal dipeptide transport system, though their clinical efficacy may be limited due to moderate potency.

Definition

ChEBI: An alpha-amino fatty acid that is caprylic acid which is substituted at position 2 by an amino group.

InChI:InChI=1S/C8H17NO2/c1-2-3-4-5-6-7(9)8(10)11/h7H,2-6,9H2,1H3,(H,10,11)

644-90-6 Relevant articles

Hexyl-modified morpholine-2,5-dione-based oligodepsipeptides with relatively low glass transition temperature

Peng, Xingzhou,Behl, Marc,Zhang, Pengfei,Mazurek-Budzyńska, Magdalena,Razzaq, Muhammad Yasar,Lendlein, Andreas

, p. 318 - 326 (2016/11/18)

Oligodepsipeptides (oDPs), alternating c...

New Aspercryptins, Lipopeptide Natural Products, Revealed by HDAC Inhibition in Aspergillus nidulans

Henke, Matthew T.,Soukup, Alexandra A.,Goering, Anthony W.,McClure, Ryan A.,Thomson, Regan J.,Keller, Nancy P.,Kelleher, Neil L.

, p. 2117 - 2123 (2016/08/30)

Unlocking the biochemical stores of fung...

Biocatalytic asymmetric synthesis of unnatural amino acids through the cascade transfer of amino groups from primary amines onto keto acids

Park, Eul-Soo,Dong, Joo-Young,Shin, Jong-Shik

, p. 3538 - 3542 (2014/01/06)

Flee to the hills: An unfavorable equili...

Microwave-assisted synthesis of unnatural amino acids

Young, Douglas D.,Torres-Kolbus, Jessica,Deiters, Alexander

experimental part, p. 5478 - 5480 (2009/05/30)

Microwave irradiation has been proven to...

644-90-6 Process route

2-leucylamino-octanoic acid

2-leucylamino-octanoic acid

L-leucine
61-90-5,21675-61-6,25248-98-0,70-45-1

L-leucine

2-aminooctanoic acid
644-90-6,2187-07-7

2-aminooctanoic acid

Conditions
Conditions Yield
bei der Einw. von Hefemacerationssaft;
2-glycylamino-octanoic acid
306748-50-5

2-glycylamino-octanoic acid

2-aminooctanoic acid
644-90-6,2187-07-7

2-aminooctanoic acid

glycine
56-40-6,18875-39-3,25718-94-9

glycine

Conditions
Conditions Yield
bei der Einw. von Hefemacerationssaft;

644-90-6 Upstream products

  • 74-90-8
    74-90-8

    hydrogen cyanide

  • 40899-00-1
    40899-00-1

    1-amino-heptan-1-ol

  • 880141-72-0
    880141-72-0

    2-formylamino-octanoic acid

  • 2623-82-7
    2623-82-7

    2-bromooctanoic acid

644-90-6 Downstream products

  • 6271-04-1
    6271-04-1

    4-hexyl-oxazolidine-2,5-dione

  • 761343-79-7
    761343-79-7

    α-hexylglycine ethyl ester

  • 92211-95-5
    92211-95-5

    2-((tertbutoxycarbonyl)amino)octanoic acid

  • 106819-03-8
    106819-03-8

    (R)-α-aminooctanoic acid

Shopping Cart

Clear Inquiry