Pharmaceutical

2-Ethoxybenzoyl chloride

  • CAS:42926-52-3
  • purity:99%
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  • Molecular Formula: C9H9ClO2
  • Molecular Weight: 184.622
  • Appearance/Colour: COLORLESS TO YELLOW TO BROWN LIQUID 
  • Vapor Pressure: 0.00677mmHg at 25°C 
  • Refractive Index: 1.553 
  • Boiling Point: 270.6 °C at 760 mmHg 
  • Flash Point: 100.8 °C 
  • PSA: 26.30000 
  • Density: 1.18 g/cm3 
  • LogP: 2.46430 

2-Ethoxybenzoyl chloride(Cas 42926-52-3) Usage

General Description

2-Ethoxybenzoyl chloride is a chemical compound with the molecular formula C10H11ClO2. It is a colorless to pale yellow liquid that is used as a reagent in organic synthesis for the preparation of esters, amides, and carboxylic acids. It is a versatile and reactive compound that is commonly used in the pharmaceutical and agrochemical industries. 2-Ethoxybenzoyl chloride is a key intermediate in the synthesis of various pharmaceutical compounds and is also used as a coupling agent in the production of dyes and pigments. It is important to handle this compound with caution, as it is corrosive and can cause severe skin and eye irritation upon contact.

InChI:InChI=1/C9H9ClO2/c1-2-12-8-6-4-3-5-7(8)9(10)11/h3-6H,2H2,1H3

42926-52-3 Relevant articles

Process for preparing O-ethoxybenzoic acid chloride (by machine translation)

-

, (2020/08/26)

The method comprises the following steps...

Hofmann Rearrangement of Carboxamides Mediated by N-Bromoacetamide

Jevti?, Ivana I.,Do?en-Mi?ovi?, Ljiljana,Ivanovi?, Evica R.,Ivanovi?, Milovan D.

, p. 1550 - 1560 (2016/06/01)

An efficient, one-pot procedure for the ...

Sedinafine derivatives of the microwave-assisted method for preparing

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Paragraph 0061, (2016/12/07)

The invention discloses a microwave-assi...

METHOD FOR PRODUCING OXAZOLE COMPOUND

-

Page/Page column 73-74, (2014/03/25)

An object of the present invention is to...

42926-52-3 Process route

methyl salicylate
119-36-8,8024-54-2

methyl salicylate

2-ethoxybenzoyl chloride
42926-52-3

2-ethoxybenzoyl chloride

Conditions
Conditions Yield
Multi-step reaction with 3 steps
1.1: potassium hydroxide / acetone / 0.5 h / 20 °C
1.2: Reflux
2.1: methanol; sodium hydroxide / 50 °C
3.1: N,N-dimethyl-formamide; phosgene / acetone / 50 °C
With methanol; phosgene; N,N-dimethyl-formamide; potassium hydroxide; sodium hydroxide; In acetone;
2-ethoxybenzoyl chloride
42926-52-3

2-ethoxybenzoyl chloride

Conditions
Conditions Yield

42926-52-3 Upstream products

  • 134-11-2
    134-11-2

    2-ethoxybenzoic acid

  • 119-36-8
    119-36-8

    methyl salicylate

42926-52-3 Downstream products

  • 16386-47-3
    16386-47-3

    2-ethoxy-benzoic acid benzo[1,3]dioxol-5-yl ester

  • 112819-13-3
    112819-13-3

    2-ethoxy-benzoic acid-(1-phenyl-2-pyrrolidino-ethyl ester); hydrochloride

  • 102476-73-3
    102476-73-3

    2-ethoxy-benzoic acid-(1-phenyl-2-piperidino-ethyl ester); hydrochloride

  • 105541-36-4
    105541-36-4

    2,5-bis-[4-(2-ethoxy-benzoylamino)-phenyl]-furan

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